High quality research calls for validated questionnaires that have been tested to accurately assess what the questionnaire claims to be assessing. The NIH has funded the development of such a tool called PROMIS ( that is accessible at no cost to the entire research community. The tool measures a variety of patient-reported areas of wellbeing. Patient-reported outcomes are gaining more and more attention as we recognize the patient perspective as equally important as measured outcomes, such as lab tests. Additionally, all studies using the PROMIS tool are stored in a central bank so that studies can be compared and combined for a meta-analysis approach, which would serve us all in the Ayurveda community very well. PROMIS has incorporated the latest statistical theories, including Itemized Response Theory. I encourage all to consider this tool in their research for all of the above reasons. Explore the website and contact them if you have any questions!